Scientists believe they may have found a way to turn cancerous cells back into healthy tissue. Their lab-based work suggests there is a biological step that can restore normality and stop cells replicating out of control. When the US researchers added molecules called microRNAs, it put the brakes on cancer, Nature Cell Biology reports. Although the early tests in a dish look promising, it is unclear whether it will help treat people with cancer. The Mayo Clinic researchers are hopeful that the new mechanism they have found could apply to all types of cancer. Putting on the brakes It brings together two strands of science – cell adhesion and microRNA (miRNA) biology – that, until now, had not been linked. Scientists had thought adhesion molecules were simply the glue that holds cells together. But then others found they might have signalling roles. The Mayo Clinic work shows adhesion molecules connect cells and signal via miRNAs to control cell growth. If this becomes deregulated it can drive cancer. But replenishing cells with miRNAs can remedy this.
Calculation of pediatric dosages are many a times cumbersome job for medical practitioners of non-pediatric branches. So, here is a simple way of calculation of pediatric drug doses.
Generally you need to know 2 things before prescribing a medicine – the dosage and the preparation in which it is available in the market.
Let’s try to explore the issue with an example.
Suppose we want to prescribe a paracetamol syrup.
First we have to calculate the dosage. So if we want to give at the dose of 15 mg/kg/dose for a 20 kg weight child the dosage will be 300 mg per dose.
Next we have to see at what strength in the market paracetamol is available. Suppose there is a preparation of paracetamol in which 120 mg paracetamol per 5 ml syrup.
So we have to calculate the amount of dosage of syrup we have to give.
A easy way to count dosage is as following-
Dose calculated/dose available x volume = 300/120 x 5 = 12.5 ml
So, 12.5 ml paracetamol is to be given per dosage to the above mentioned example.
By using the formula above almost any drugs dosage can be derived.
A French woman has won a disability grant after telling a court she suffers from an allergy to electromagnetic radiation from gadgets. Marine Richard, 39, was told she may claim €800 (£580) per month for three years as a result. She said it was a “breakthrough” for people affected by electromagnetic hypersensitivity (EHS). The condition is recognised by the World Health Organisation (WHO), though it says the causes are unclear. Ms Richard had resorted to living in a remote area in the mountains of south-west France – in a barn that has no electricity. She said she had been affected by everyday gadgets such as phones. Typical symptoms reported by those who say they suffer from EHS include headaches, fatigue, nausea and palpitations. Continue reading
Oral polio drops are most popular for its use in various immunization camps organized by various health organizations around the world, particularly in 3rd world nations. However, where economic constraints are not an issue polio vaccine injections are also used.
The oral vaccine rarely causes vaccine associated paralytic polio, in view of which certain developed nations are not using oral polio vaccine anymore, instead using injectable polio vaccine. Continue reading
More than 300,000 members of India’s Patel community have staged a rally in Gujarat demanding better access to jobs and education.
The rally in Ahmedabad city was addressed by Hardik Patel, a 21-year-old controversial community leader.
The rally turned violent when protesters clashed with local residents, including some from lower-caste groups
Patels make up 20% of the population of Gujarat, the home state of Prime Minister Narendra Modi.
The caste is economically powerful but the protesters say quotas for lower castes put them at a disadvantage. Continue reading
God or mother nature probably created everything on earth for a good reason to continue the flow of life. Unfortunately we humans are always the main culprits to make wrong use of things that we got from mother nature. The plant cannabis had always been used by man as a substance abuse drug and so many crimes have taken place in relation to its abuse and farming.
Now at the dawn of 21st century we are getting the clues about the good side of these substance abusing agents. Already opium’s goodness is established in decreasing pain in terminally ill cancer patients etc. Recently US government confirmed that cannabinoid a component of cannabis can kill cancer cells in mice and rats, however there effectiveness on human cancer cells are yet to be proven. Nevertheless, this doesn’t mean cancer patients should start taking cannabis. You need to wait with time until some definite info in this regard becomes available. Continue reading
Sharing childcare makes for happier couples with better sex lives, US research suggests.
In a study of 487 families, parents who split childcare duties evenly reported greater satisfaction, both sexually and emotionally.
But in couples where the woman did most of the childcare, both men and women reported being less content.
The researchers said men doing a greater share of childcare did not have the same impact. Continue reading