What is the role of angiotensin II?

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Angiotensin II is the by-product of angiotensin I.

Its roles are as the following:

  1. Increase sodium and water retention and potassium excretion via its action on adrenal gland’s (a cap like structure placed above both of the kidneys) cortex region’s outer portion i.e. the zona glomerulosa by secreting aldosterone

  2. Act on hypothalamus and produce cause increase in thirst.

  3. Act on peripheral vessels and constrict them, to raise the blood pressure

  4. Constricts efferent arteriole of glomerulus and attempt to maintain glomerular filtration rate even at low BP states

  5. Act on posterior pituitary gland and cause release of ADH (antidiuretic hormone). ADH help is reabsorption of water at distal tubules by inserting water passing channels (also called aquaporins).

Related: What is Renin angiotensin aldosterone system?

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