Tag Archives: Insulin

Why insulin requirement decreases in diabetes patients with long term kidney disease?

Those people who are suffering from diabetes and taking insulin probably become happy when their doctor decreases their dose of insulin or stops insulin.

But if a person is suffering from chronic kidney disease along with diabetes, decrease in insulin doses may not be something to be happy.

When chronic kidney disease deteriorates i.e. progresses to advanced stages, the requirement of insulin falls in diabetics.

Now the question is:

Why insulin requirement falls in advanced stages of chronic kidney disease?


  • In advanced stages of chronic renal failure, the kidneys excretion capacity of insulin molecules decrease, therefore more of the insulin remains in blood. Unless the insulin gets excreted normally the further requirement of insulin is less. In such scenario your doctor might decrease your insulin doses.

Ask you doctor today to be sure why your insulin dose was decreased.


Why insulin is needed for our body?

Insulin is a hormone produced by our pancreas (an organ found in our abdomen). Insulin stores the sugar, fat and protein that we take through our diet.

When the body is lacking insulin or insulin in not able to work efficiently, as in case of diabetes, sugar can’t be stored in our body anymore and hence the level of the sugar in blood increases.

At certain times the fat level in blood can rise due to deficiency of insulin, causing a condition called ketoacidosis (since free fatty acids break down to ketone bodies and makes our body acidic).

Therefore, for our body to function properly insulin is required. Insulin can be taken in injectable forms, beneath our skin, when needed.

For all your health concerns be guided your health care provider and not this blog.

Tests to diagnose diabetes

Diagnosing diabetes-

Blood sugar levels which refers an individual as diabetic are as following (although one such reading might not be sufficient and other clinical features might be included in making a diagnosis)-

  • Fasting >126mg/dl
  • Random >200mg/dl
  • HbA1C (glycated hemoglobin) >6.5
  • For diagnosis of gestational diabetes your doctor may need another test called glucose tolerance test in which you will be given certain amount of glucose drink and then checking your blood sugar levels after certain intervals.

Cross check the levels from other sources too.

Type 2 diabetes

Type 2 diabetes:

  1. This disease primarily occur in adults and elderly persons with family history of type 2 diabetes. The condition also associated obesity, sedentary lifestyle, high calorie sugary and fatty diet, lack of exercise etc.
  2. In contrast to type 1 this variant is not necessarily due to a deficiency (although a decreased secretion from pancreas might be present) rather due to insulin resistance. Exact causes are yet to be discovered.
  3. This type is primarily treated with dietary modification and exercises sometimes along with antidiabetic medications. When these therapies fail an insulin therapy is generally planned.
  4. An emergency condition of type 2 also exists called hyperosmolar non-ketotic coma (not going in details of it here).

Continue reading Type 2 diabetes

Type 1 diabetes

Type 1 diabetes

This type is usually of juvenile type i.e. occurs in young aged children or adolescents.
Type 1 occurs due to true deficiency of the hormone insulin.

Now the question is why should someone be deficient to the hormone. Any serious insult to the pancreas (in the beta cells of pancreas mainly, where insulin is produced) can damage its ability to produce insulin. Since there is true deficiency of insulin it’s also called insulin dependent type of diabetes. Continue reading Type 1 diabetes

Diabetes basic talks

Diabetes is a disease condition where blood glucose levels are persistently above the normal level and generally diagnosed by a doctor using an individual’s medical history, clinical findings and certain laboratory tests.

Diabetes is primarily of 2 types – type 1 and type 2. Before describing each of this type let me share a snapshot about of the normal physiology of humans, which might serve as a good appetizer before the main dish. In our abdomen we have an organ named pancreas, which is responsible for production of hormones like insulin, glucagon, somatostatin etc. Insulin, primarily decrease the blood glucose level to keep the blood glucose level optimum and glucagon does the opposite, raises the blood glucose level and normally there is a harmony between their actions.

For various types check the following links:Type 1 diabetes,  Type 2 diabetes

Breast milk decrease in prediabetes

After the pregnancy is over many mothers face a problem of decreased breast milk production and can’t feed their newborn fully. There are various myths associated to this too. Interestingly breast milk production seems to be connected to the mothers health directly. New findings suggest that female breast during lactation can produce such huge quantity of milk with the help of a hormone connected to diabetes, i.e. insulin. Insulin is a hormone made in our pancreas, which plays role in introducing protein, fat and carbohydrate in the breast milk since it has anabolic role (i.e. storage type role, insulin stores fat, protein and sugar instead of degrading them).

Therefore, if a women is prediabetic her insulin function will be abnormal hence the amount of breast milk produced might decrease too. So if the prediabetes is taken care of in time, nourishing the baby might not be a problem. Simple steps of diet and exercise may ease the situation a lot. Even if you have diabetes don’t self medicate yourself since diabetic drugs are harmful for the baby and only a specific one is used henceforth, approach to a doctor to seek expert help.
A baby having milk from a bottle.

Please cross check information from other sources too. For all your health concerns please be guided by your healthcare provider. References: http://www.nlm.nih.gov/medlineplus/news/fullstory_138459.html